A Case of Multicentric Reticulohistiocytosis

multicentric reticulohistiocytosis: a case report

multicentric reticulohistiocytosis (mrh) is a rare proliferative histiocytic disease of ‎unknown cause with potentially disabling nature. primary manifestations are involvement ‎of skin and joints. the articular destruction can lead to permanent joint deformities. our ‎patient was a 47 year-old woman with bilateral symmetrical polyarthritis and reddish- ‎brown papulonodular cutaneous lesions. t...

Progressive multicentric reticulohistiocytosis.

Multicentric Reticulohistiocytosis Associated with Liver Carcinoma: Report of a Case

We report a unique case of multicentric reticulohistiocytosis (MRH) associated with liver carcinoma. A 61-year-old man presented with a 4-month history of nonpruritic, generalized, ruby-red papules and nodules, accompanied by fever, joint swelling and difficulty in swallowing. Skin histology showed polymorphic histiocyte infiltration with typical 'ground glass' cytoplasm. Further immunohistoche...

Multicentric reticulohistiocytosis with extra-mammillary Paget’s disease: a case report

Multicentric reticulohistiocytosis (MRH) is a very rare systemic disease with variable phenotypic presentation and a high rate of misdiagnosis. Here we describe a patient with MRH and extra-mammillary Paget's disease (EMPD), a diagnosis that has not previously been described in the literature.

Multicentric reticulohistiocytosis with S100 protein positive staining: a case report.

Multicentric reticulohistiocytosis is a very rare systemic disease that affects skin, mucosa and joints. We reported a case of a woman with multicentric reticulohistiocytosis who presented typical skin syndromes and arthralgia. Immunohistochemical analysis showed positive staining for S100 protein, which was reported negative in the majority of previously presented cases. Other immunohistochemi...